Biomarkers of Environmental Toxicants

• Andere auteurs: LU, Kun (Redacteur), Turesky, Robert J. (Redacteur)
• Formaat: Elektronisch Hoofdstuk
• Taal: Engels
• Gepubliceerd in: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Onderwerpen: Medicine; manganese; lead; cadmium; arsenic; hair; children; environment; carcinogen; DNA adducts; biomonitoring; formalin-fixed paraffin-embedded tissues; biomarker; mass spectrometry; human biomonitoring; urine; non-occupational exposure; S-phenyl-mercapturic acid; HPLC-MS/MS; glycidol; Hb adduct; N-(2.3-dihydroxypropyl)valine; in vivo; cancer risk; UPLC/MS/MS; aristolochic acids; food contamination; environmental pollution; root uptake; aristolochic acid nephropathy; Balkan endemic nephropathy; chronic kidney disease; tobacco smoke; human carcinogen; biomarkers; epitranscriptomics; tRNA modifications; stress response mechanisms; codon-biased translation; phthalate; DEHP; human exposure; toxicity; reproductive; accelerator mass spectrometry; cavity ring down spectrophotometry; radiocarbon; naphthalene; benzo[a]pyrene; cell turnover; triclocarban; metastasis; haemoglobin; albumin; protein adducts; aldehydes; genotoxicity; cancer; diseases; oxidative stress; exposure biomarkers; high-resolution mass spectrometry; data-dependent profiling; derivatization; biological fluids; isotope labeling; DNA lesion; DNA damage; shuttle vector technique; replication block; mutagenicity; mutational spectrum; mutational signature; DNA repair; DNA adduct bypass; site-specific mutagenesis; chemical exposome; environmental monitoring; disease; bioinformatics; gut microbiome; chemical toxicity; n/a
• Online toegang: DOAB: download the publication; DOAB: description of the publication

Biomarkers of environmental toxicants are measures of exposures, some of which can serve to assess disease risk and inter-individual susceptibilities. Metabolites, protein and DNA adducts also serve to elucidate the mechanisms of the bioactivation and detoxication of reactive toxicant intermediates....