Male Germline Chromatin

• Other Authors: Griffin, Darren (Editor), Ellis, Peter (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Research & information: general; Biology, life sciences; mouse sperm chromatin; chromosome organization; nuclear-3D-parameters; spermiogenesis; chromatin remodeling; DNA double-strand breaks; genetic instability; mutations; sperm DNA damage; DNA fragmentation; infertility; assisted reproduction; miscarriage; implantation; nuclear organization; sperm; morphometrics; chromosome painting; nucleoli; NOR; chromosome associations; meiotic prophase; spermatocytes; Mus m. domesticus; Robertsonian chromosomes; chromosome translocation; Y chromosome; testis; spermatogenesis; SLY; mouse; oxidative stress; reactive oxygen species; chromatin; DNA oxidation; male infertility; spermatozoa; chromosomes; chromosome territories; centromeres; male germ cells; telomeres; reproductive aging; nuclear organisation; epigenetic inheritance; histone retention; in vitro fertilisation
• Online Access: DOAB: download the publication; DOAB: description of the publication

Spermatogenesis requires radical restructuring of germline chromatin at multiple stages, involving coordinated waves of DNA methylation/demethylation, histone modification, and the replacement and removal that occurs before, during, and after meiosis. This Special Issue will draw together papers tha...