Bacteriophages Alternatives to Antibiotics and Beyond

• Other Authors: Suárez, Pilar García (Editor), Fernández, Lucía (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; bacteriophages; dairy industry; pathogens; lactic acid bacteria; fermentation failure; biofilms; antimicrobial resistance; antimicrobials; lysins; horizontal gene transfer, transduction; biofilm; phage therapy; resistance; bacteriophage; models; agent based; mass action; bacterial phage resistance; regression modeling; MRSA; Clostridium difficile; Clostridium difficile infection; microbiome; in vitro fermentation model; marine vibrios; biological control; aquaculture; interactions; vibriosis; Aeromonas hydrophila; Motile Aeromonas Septicemia; MAS; multiple-antibiotic-resistance; striped catfish (Pangasianodon hypophthalmus); endolysin; antibiotics; one health; protein engineering; Aeromonas salmonicida; furunculosis; phage-resistant mutants; proteins; infrared spectroscopy; lysin; lytic enzyme; peptidoglycan hydrolase; antimicrobial; antibacterial; antibiotic resistance; bacteriophage therapy; Nagoya Protocol; CRISPR CAS; phage isolation; phage resistance; Staphylococcus; Kayvirus; Vibrio anguillarum; fish larvae; challenge trials; phage display; enzybiotics; Bacteriophages; diabetic foot ulcer; osteomyelitis; Staphylococcus aureus; Antibiotic-resistant bacteria; lysogenic conversion; prophage induction; read recruitment; shiga toxin; American Foulbrood; phage; Paenibacillus larvae; Brevibacillus laterosporus; treatment; safety; bystander phage therapy; Mycobacterium smegmatis; mycobacteriophages; directed evolution; PlyC CHAP; protein net charge; CBD-independent; FoldX; STEC-specific bacteriophage; whole genome sequencing; STEC O145 strains; antimicrobial agent; Pseudomonas aeruginosa; dual-species; antibiotic; synergy; simultaneous; sequential; microbiome therapy; evolution
• Online Access: DOAB: download the publication; DOAB: description of the publication

There is talk of an upcoming antibiotic armageddon, with untreatable post-operative infections, and similarly untreatable complications after chemotherapy. Indeed, the now famous "O'Neill Report" (https://amr-review.org/) suggests that, by 2050, more people might die from antibiotic-r...