mTOR Signaling in Metabolism and Cancer

• Other Authors: Huang, Shile (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; mTOR; histone deacetylase; prostate cancer; integrins; adhesion; invasion; cell metabolism; T cells; Foxp3; Acute Lymphoblastic leukemia; targeted therapy; metabolism; cell signalling; mTOR signalling; head and neck cancer; mutant genes; biomarkers; targeted therapies; clinical trials; cancers; inhibitors; photodynamic therapy; PI3K; Akt; skin cancers; phytochemicals; melanoma; basal cell carcinoma; squamous cell carcinoma; Merkel cell carcinoma; TNBC; eribulin; PI3K/AKT/mTOR; everolimus; combination; synergy; mTOR signaling; tissue regeneration; neuron; muscle; liver; intestine; hematologic malignancies; regulatory T cells; tumor
• Online Access: DOAB: download the publication; DOAB: description of the publication

The mechanistic/mammalian target of rapamycin (mTOR), a serine/threonine kinase, is a central regulator for human physiological activity. Deregulated mTOR signaling is implicated in a variety of disorders, such as cancer, obesity, diabetes, and neurodegenerative diseases. The papers published in thi...