Autophagy in Tissue Injury and Homeostasis

• Other Authors: Lin, Pei-Hui (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2020
• Subjects: Medicine; aging; dietary restriction; acute kidney injury; mitochondria; autophagy; mitophagy; ischemia; renal tubular cells; diabetic nephropathy; exosomes; mTOR; innate immunity; immune cell; inflammasome; Paneth cell; inflammatory bowel disease; Crohn's disease; hepatocytes; hepatic stellate cells; sinusoidal endothelial cells; macrophages; fibrosis; cirrhosis; hepatocellular carcinoma; biomarkers; cell death; glutaminase; metabolism; molecular rehabilitation.; kidney diseases; oxidative stress; inflammation; ATGs; intestinal homeostasis; inflammatory bowel diseases; HCC therapy; Autophagy; acute lung injury; idiopathic pulmonary fibrosis; COPD; tuberculosis; PAH; cystic fibrosis; Beclin-1; cardiac dysfunction; sepsis; endotoxemia; muscle regeneration; stem cell; immune; macrophage; senescence; exercise; caloric restriction; diabetic retinopathy; PINK1; Notoginsenoside R1; ethanol; LC3; apoptosis; Sertoli cell; Parkin; TFEB; infertility; AMPK; FOXO; MTOR; parkin; spinal cord injury; traumatic brain injury; autophagic flux; neuronal cell death; lysosomal damage; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Autophagy ("auto-digestion"), a lysosome-dependent process, degrades and turns over damaged or senescent organelles and proteins. Autophagy is a highly regulated process that impacts several vital cellular responses, including inflammation, cell death, energy metabolism, and homeostasis of...