G Protein-Coupled Receptor Kinases (GRKs) and Beta-Arrestins: New Insights into Disease Regulators

• Diğer Yazarlar: Hattori, Yuichi (Editör), Michel, Martin C. (Editör)
• Materyal Türü: Elektronik Kitap Bölümü
• Dil: İngilizce
• Baskı/Yayın Bilgisi: Frontiers Media SA 2020
• Konular: Science: general issues; Pharmacology; GRK; beta-arrestins; cardiovascular; inflammation; cancer
• Online Erişim: DOAB: download the publication; DOAB: description of the publication

G protein-coupled receptor kinases (GRKs) and arrestins were initially identified as a pivotal player in the process of desensitization of agonist-activated G protein-coupled receptors (GPCRs). However, growing evidence suggests GRKs and arrestins fulfill a vital role in regulating a variety of cell...