Shankopathies: Shank Protein Deficiency-Induced Synaptic Diseases

• Altri autori: Ey, Elodie (Redattore), Bourgeron, Thomas (Redattore), Maria Boeckers, Tobias (Redattore), Kim, Eunjoon (Redattore), Han, Kihoon (Redattore)
• Natura: Elettronico Capitolo di libro
• Lingua: inglese
• Pubblicazione: Frontiers Media SA 2020
• Soggetti: Science: general issues; Neurosciences; Shank; Shankopathies; neuropsychiatric disorders; modulating factors; brain regions
• Accesso online: DOAB: download the publication; DOAB: description of the publication

Shank (also known as ProSAP) is a family of postsynaptic scaffolding proteins that are thought to be involved in the regulation of excitatory synapse development, function, and plasticity. The Shank family contains three known members (Shank1, Shank2, and Shank3). These proteins are equipped with va...