Vitamin D Binding Protein, Total and Free Vitamin D Levels in Different Physiological and Pathophysiological Conditions

• Other Authors: David Bikle, Daniel (Editor), Xie, Zhongjian (Editor), Wang, Xiangbing (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Frontiers Media SA 2020
• Subjects: Medicine; Endocrinology; vitamin D binding protein; total 25-hydroxyvitamin D; free 25-hydroxyvitamin D; 1; 25-dihydroxyvitamin D; bioavailable 25-hydroxyvitamin D
• Online Access: DOAB: download the publication; DOAB: description of the publication

There is a high prevalence of vitamin D deficiency worldwide, but how to define vitamin D deficiency is controversial. Currently, the plasma concentration of total 25-hydroxyvitamin D [25(OH)D] is considered an indicator of vitamin D status. The free hormone hypothesis states that protein-bound horm...