The Protein Alpha-Synuclein: Its Normal Role (in Neurons) and its Role in Disease

• Otros Autores: Manfredsson, Fredric P. (Editor), Perez, Ruth G. (Editor), Martinez Sandoval, Ivette (Editor)
• Formato: Electrónico Capítulo de libro
• Lenguaje: inglés
• Publicado: Frontiers Media SA 2020
• Materias: Science: general issues; Neurosciences; alpha-synuclein function; alpha-synuclein aggregation; neurodegeneration; Parkinson's disease; synucleinopathies
• Acceso en línea: DOAB: download the publication; DOAB: description of the publication

The protein alpha-synuclein (α-syn) is by far the most vetted pathogenic participant in the neurodegeneration that occurs in Parkinson's disease (PD) and other synucleinopathies such as multiple system atrophy (MSA). Although the precise role of this protein in disease pathogenesis is unknown,...