The Protein Alpha-Synuclein: Its Normal Role (in Neurons) and its Role in Disease

• अन्य लेखक: Manfredsson, Fredric P. (संपादक), Perez, Ruth G. (संपादक), Martinez Sandoval, Ivette (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Frontiers Media SA 2020
• विषय: Science: general issues; Neurosciences; alpha-synuclein function; alpha-synuclein aggregation; neurodegeneration; Parkinson's disease; synucleinopathies
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

The protein alpha-synuclein (α-syn) is by far the most vetted pathogenic participant in the neurodegeneration that occurs in Parkinson's disease (PD) and other synucleinopathies such as multiple system atrophy (MSA). Although the precise role of this protein in disease pathogenesis is unknown,...