Centenarians-A Model to Study the Molecular Basis of Lifespan and Healthspan

• Other Authors: Puca, Annibale (Editor), Caruso, Calogero (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Research & information: general; Biology, life sciences; aging; alternative therapy; composition of royal jelly; dietary interventions; healthspan; lifespan; longevity; royal jelly; IGF-1; oxidative stress; ageing; nematode; immunosenescence; probiotic bacteria; pathogen protection; food allergy; elderly; hypersensitivity; gut; allergy; inflammation; redoxomics; glutathione; meniere's disease; neurodegenerative diseases; healthy aging; DNA methylation; epigenetic clocks; telomere length; centenarians; exosomes; serum; functional enrichment analysis; ingenuity pathway analysis; miRNA-mRNA networks; aging-related disease; Di (2-Ethylhexyl) pthalate; Hericium erinaceus; vitagenes; apoptosis; mitochondrial respiratory complexes; C. elegans; polyphenols; olive oil; Parkinson's disease; β-Dystroglycan; cellular senescence; lamin B1; DNA-damage response; defective mitosis; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

People around the world are living longer. For the first time in history, most humans will live to be sixty and beyond. By 2050, the world's population aged 60 and over will reach a total of 2 billion, up from 900 million in 2015. Today, 125 million people are 80 years of age or older. By 2050,...