Recent Developments in Cancer Systems Biology

• Other Authors: Sinha, Raghu (Editor), Arga, Kazim Yalcin (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; Sestrin2; lung cancer; knockdown; cancer progression; bioinformatics; patient survival; lung adenocarcinoma; circulating miR-1246; glycosaminoglycan binding; prognosis; PI3K-Akt signaling pathways; TargetScan; UBE2C; cancer systems biology; experimental model systems; next-generation sequencing; single-cell sequencing; patient-derived xenografts; patient-derived organoids; triple-negative breast cancer; personalized medicine; computational methods; drug repurposing; clinical trials; cancer stem cells; ETS; Elk-1; stem cell; microarray; brain-tumor-initiating cell (BTIC); pancreatic cancer; systems biology; omics; biomarker; genomics; transcriptomics; proteomics; metabolomics; glycomics; metagenomics; Ets; PEA3; Ets-1; glioma; optical genome mapping; solid tumors; cancer genomics; breast; ovarian; cancer; TCGA; non-small-cell lung cancer; lung adenocarcinoma (LUAD); lung squamous cell carcinoma (LUSC); differential expression; SNV; CNV; risk group; signature; survival; renal cancers; protein interactome; diagnostic biomarker; prognostic biomarker; virtual screening; docking; acute myeloid leukemia; Boolean model; drug resistance; network; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

This ebook includes original research articles and reviews to update readers on the state of the art systems approach to not only discover novel diagnostic and prognostic biomarkers for several cancer types, but also evaluate methodologies to map out important genomic signatures. In addition, therap...