Crocus sativus L. Extract and Its Constituents: Chemistry, Pharmacology and Therapeutic Potential

• Other Authors: Pitsikas, Nikolaos (Editor), Dimas, Konstantinos (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; saffron; affron®; depression; anxiety; antioxidant; crocins; glucose; β-pancreatic cells; insulin; pck1; neuroprotective activity; P2X7 receptor; fraction; flumazenil; rat; Crocus sativus; cancer; anticancer activity; chemoprevention; clinical trials; patents; anesthetic ketamine; memory; Crocus sativus L.; schizophrenia; crocetin; pubertal testis; X-rays; radiotherapy; fertility preservation; SIRT1; HuR; oxidative stress; autophagy; crocin; picrocrocin; safranal; dietary supplement; nutraceutical; Crocus sativus L. (Iridaceae); reversed-phase UPLC; metabolomics; HR MS; inflammatory bowel disease; gut microbiota; colitis; cytokines; colorectal cancer; HCT116; MLH1; MSH3; DNA damage and repair; apoptosis; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Natural products or organic compounds isolated from natural sources as primary or secondary metabolites have inspired numerous drugs. It is not an overstatement that the majority of medicines in clinics, even in the 21st century, have been derived from natural resources despite the decline of indust...