Marine Natural Products as Anticancer Agents

• Other Authors: Alves, Celso (Editor), Diederich, Marc (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; alga; marine-derived fungus; Penicillium chrysogenum; polyketide; hydroxyphenylacetic acid; cytotoxicity; flaccidoxide-13-acetate; hepatocellular carcinoma; invasion; migration; epithelial-mesenchymal transition; prostate cancer; astaxanthin; STAT3; proliferation; colony formation; apoptosis; Sarcophyton digitatum; biscembranoid-type metabolites; inflammatory factor production; LPS-stimulated murine macrophage; Ehlich's tumor; P. purpurogenum; antitumor; meroterpenoids; inflammation; T47D; BT20; pontin; mutp53; cancer stem cells; Oct4; Nanog; siRNA; secondary metabolites; epigenome; epigenetic signaling; bioactive compounds; cancer therapy; marine species; environment; total synthesis; natural product; nannocystin; anti-cancer; gram-scale; aplysinopsin analogs; indole alkaloids; marine source; chronic myeloid leukemia; BH3 mimetics; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Cancer remains one of the most significant threats to human health and one of the deadliest diseases worldwide, making it crucial to develop new drugs. Over the last few decades, natural products have become one of the key drivers in the development of innovative cancer treatments. Despite drug deve...