Small Cell Lung Cancer: A New Era Is Beginning?

• Other Authors: Morabito, Alessandro (Editor), Rolfo, Christian (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; immune checkpoint inhibitors; extensive-stage small cell lung cancer; nivolumab; ipilimumab; pembrolizumab; atezolizumab; durvalumab; chemotherapy; small-cell lung cancer; lobectomy; pneumonectomy; radiotherapy; multimodal treatment; immunotherapy; SCLC; PARP; DDR; ICB; synthetic lethality; SLFN11; STING; pathology and classification of SCLC; biology of SCLC; immune-checkpoint inhibitors in SCLC; small cell lung cancer; Immunotherapy; extensive disease; lurbinectedin; gene pathway; pathobiology; targeted therapy; circulating tumor cells; prognostic biomarker; targeted agents; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Small-cell lung cancer (SCLC) is the most aggressive form of lung cancer: No significant progress has been made in finding new treatments for decades and platinum-based chemotherapy has for a long time represented the standard of care. This therapeutic scenario has recently changed, thanks to positi...