Multi-Omics for the Understanding of Brain Diseases

• Other Authors: Yoon, Jong (Editor), Villa, Chiara (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Research & information: general; schizophrenia; abnormal behavior gene set; region; differentially expressed genes; de novo mutation; copy number variant; SIDS; newborn infant; genetic polymorphism; neurotransmitter; epigenetics; epigenome; zinc finger domain; zinc finger motif; zinc finger proteins; zinc metalloproteins; flow infusion analysis; chloride adducts; ceramides; sphingolipids; glycerophosphocholines; human brain; NAD+; nicotinamide; ageing; plasma; biomarker; CNV; PPI; spatiotemporal network; chromosome 22q11.21; DGCR8; Orthosiphon stamineus; plant-derived proteins; neuroprotective; SH-SY5Y cell model; hydrogen peroxide; CSF; miRNAs; neurological diseases; OpenArray; morphine; withdrawal; brain; proteomics; synaptic plasticity; Alzheimer's disease; microfluidics; lab-on-chip; 3D culture; organ-on-chip; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Omics technologies such as proteomics, genomics, and metabolomics are widely applied for the identification and characterization of new molecular signatures. However, molecular profiling that makes it possible to understand neurodegenerative diseases has been relatively insufficient. Brain diseases...