Systemic Autoinflammatory Diseases-Clinical Rheumatic Challenges

• Other Authors: Feist, Eugen (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute 2021
• Subjects: Medicine; gout; febuxostat; colchicine; hepatotoxicity; prophylaxis; myositis; inflammatory idiopathic myopathy; dysphagia; aspiration; pneumonia; immunoglobulin G4-related orbital disease (IgG4-ROD); orbital lymphoma (OL); computed tomography (CT); Hounsfield unit; imaging; autoinflammation; arthritis; CAPS; FCAS; MWS; CINCA; NOMID; hearing loss; urticarial-like rash; autoinflammatory disease; anti-IL-1 treatment; rheumatoid arthritis; synovitis; neoplasms; edema; inflammation; new genetic variant; monogenic autoinflammatory syndrome; diagnostic delay; anakinra; damage index; genetic inheritance; personalized therapy; Interleukin-1; autoinflammatory diseases; FMF; coronavirus; SARS-CoV-2 antibody response; adult-onset Still's disease; autoinflammatory disorder; systemic-onset juvenile idiopathic arthritis; haemophagocytic lymphohistiocytosis; macrophage activation syndrome; IFN-γ; JAK inhibitor; proliferation; DNA damage repair; γH2AX; PBMCs; T lymphocytes; proteasome; autoimmune; proteasome-associated autoinflammatory syndrome; therapy; IL-1 inhibitors; NGS; SURF; spondyloarthritis; human leukocyte antigen; undifferentiated enthesitis and/or arthritis; ASAS classification criteria; clinical management; canakinumab; cytokines; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Autoinflammation, as a relatively new field in clinical rheumatology, has gained an increasing importance in recent years. The number of identified entities and affected patients has gradually increased, and some of the involved pathways have already been identified. This progress allows a deeper un...