Solid Dispersions for Drug Delivery Applications and Preparation Methods

• Kolejni autorzy: Khutoryanskiy, Vitaliy (Redaktor), Al-Obaidi, Hisham (Redaktor)
• Format: Elektroniczne Rozdział
• Język: angielski
• Wydane: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Hasła przedmiotowe: Medicine; Pharmaceutical industries; solid dispersions; drug delivery; biological applications; solid dispersion; delivery system; polymeric carriers; antichagasic activity; fexofenadine hydrochloride; PEG 20,000; poloxamer188; dissolution; absorption; green nanotechnology; raloxifene; nanoemulsion; core-sheath nanofibers; response surface methodology; ex vivo drug permeation; in vivo pharmacokinetic studies; acalabrutinib; amorphous solid dispersion; acid-reducing agent; bioavailability enhancement; kinase inhibitor; pH effect; proton pump inhibitor; spray drying; hydrogen bonding; hydrophobicity; poly(N-vinyl pyrrolidone); poly(2-oxazolines); crystallinity; hydrophobic drug; amorphous; ibuprofen; drug-rich phase; liquid-liquid phase separation; permeability enhancement; cocrystals; coamorphous; solubility; dry powder inhalers; pulmonary drug delivery; acid reducing agent; in silico prediction; absorption modeling; GastroPlus; paroxetine; nanosuspension; oral fast dissolving film; factorial design; rapid release; ex vivo permeation; bioavailability; n/a
• Dostęp online: DOAB: download the publication; DOAB: description of the publication

Streszczenie

Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions for different therapeutic applications. This book can be particularly useful for researchers as well as postgraduate students in formulation sciences and drug delivery. Undergraduate students will also find elements of this book very relevant to scientific fundamentals such as solubility and crystallization of amorphous materials as well as drug delivery challenges.

Opis fizyczny

1 electronic resource (243 p.)

ISBN

books978-3-0365-2638-6
9783036526386
9783036526393

Ograniczenie dostępu

Open Access