Solid Dispersions for Drug Delivery Applications and Preparation Methods

Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions fo...

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Other Authors: Khutoryanskiy, Vitaliy (Editor), Al-Obaidi, Hisham (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
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DOAB: description of the publication
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520 |a Since their first application in the improvement of solubility of orally delivered drugs, applications of solid dispersions have considerably expanded to include cancer, infections, and inflammatory conditions. This book presents recent advancements in the development and use of solid dispersions for different therapeutic applications. This book can be particularly useful for researchers as well as postgraduate students in formulation sciences and drug delivery. Undergraduate students will also find elements of this book very relevant to scientific fundamentals such as solubility and crystallization of amorphous materials as well as drug delivery challenges. 
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650 7 |a Medicine  |2 bicssc 
650 7 |a Pharmaceutical industries  |2 bicssc 
653 |a solid dispersions 
653 |a drug delivery 
653 |a biological applications 
653 |a solid dispersion 
653 |a delivery system 
653 |a polymeric carriers 
653 |a antichagasic activity 
653 |a fexofenadine hydrochloride 
653 |a PEG 20,000 
653 |a poloxamer188 
653 |a dissolution 
653 |a absorption 
653 |a green nanotechnology 
653 |a raloxifene 
653 |a nanoemulsion 
653 |a core-sheath nanofibers 
653 |a response surface methodology 
653 |a ex vivo drug permeation 
653 |a in vivo pharmacokinetic studies 
653 |a acalabrutinib 
653 |a amorphous solid dispersion 
653 |a acid-reducing agent 
653 |a bioavailability enhancement 
653 |a kinase inhibitor 
653 |a pH effect 
653 |a proton pump inhibitor 
653 |a spray drying 
653 |a hydrogen bonding 
653 |a hydrophobicity 
653 |a poly(N-vinyl pyrrolidone) 
653 |a poly(2-oxazolines) 
653 |a crystallinity 
653 |a hydrophobic drug 
653 |a amorphous 
653 |a ibuprofen 
653 |a drug-rich phase 
653 |a liquid-liquid phase separation 
653 |a permeability enhancement 
653 |a cocrystals 
653 |a coamorphous 
653 |a solubility 
653 |a dry powder inhalers 
653 |a pulmonary drug delivery 
653 |a acid reducing agent 
653 |a in silico prediction 
653 |a absorption modeling 
653 |a GastroPlus 
653 |a paroxetine 
653 |a nanosuspension 
653 |a oral fast dissolving film 
653 |a factorial design 
653 |a rapid release 
653 |a ex vivo permeation 
653 |a bioavailability 
653 |a n/a 
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