Monoclonal Antibody-Directed Therapy

• Other Authors: Kayser, Veysel (Editor), Datta-Mannan, Amita (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Pharmaceutical industries; therapeutic antibody; stability; aggregation; manufacture challenges; formulation; antibodies; site-specific conjugation; bioconjugates; ADC; antibody-drug conjugates; payloads; linkers; nucleic acids; ADME; developability; glycosylation; post-translational modifications; pharmacokinetics; effector functions; antibody-dependent cell-mediated cytotoxicity; complement-dependent cytotoxicity; immunogenicity; pharmacodynamics; glycoengineering; type III secretion system; prophylaxis; antibacterials; antibiotics; HIV/AIDS; co-formulation; high concentration; analytical characterization; antibody (s); T-cell engagers; bispecific antibodies; immunotherapy; oncology; antibody engineering; immunological synapse
• Online Access: DOAB: download the publication; DOAB: description of the publication

The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading group...