Monoclonal Antibody-Directed Therapy

The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading group...

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Bibliographic Details
Other Authors: Kayser, Veysel (Editor), Datta-Mannan, Amita (Editor)
Format: Electronic Book Chapter
Language:English
Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
Subjects:
Online Access:DOAB: download the publication
DOAB: description of the publication
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520 |a The book deals with therapeutic monoclonal antibodies (mAbs) broadly, and relevant topics such as challenges and opportunities, next-generation antibody products, Antibody-Drug-Conjugates (ADC), bispecifics, glycosylation, and T-cell engagers are covered. Each topic has been written by leading groups around the world and the book should be of interest to researchers from both academia and industry. 
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650 7 |a Medicine  |2 bicssc 
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653 |a therapeutic antibody 
653 |a stability 
653 |a aggregation 
653 |a manufacture challenges 
653 |a formulation 
653 |a antibodies 
653 |a site-specific conjugation 
653 |a bioconjugates 
653 |a ADC 
653 |a antibody-drug conjugates 
653 |a payloads 
653 |a linkers 
653 |a nucleic acids 
653 |a ADME 
653 |a developability 
653 |a glycosylation 
653 |a post-translational modifications 
653 |a pharmacokinetics 
653 |a effector functions 
653 |a antibody-dependent cell-mediated cytotoxicity 
653 |a complement-dependent cytotoxicity 
653 |a immunogenicity 
653 |a pharmacodynamics 
653 |a glycoengineering 
653 |a type III secretion system 
653 |a prophylaxis 
653 |a antibacterials 
653 |a antibiotics 
653 |a HIV/AIDS 
653 |a co-formulation 
653 |a high concentration 
653 |a analytical characterization 
653 |a antibody (s) 
653 |a T-cell engagers 
653 |a bispecific antibodies 
653 |a immunotherapy 
653 |a oncology 
653 |a antibody engineering 
653 |a immunological synapse 
856 4 0 |a www.oapen.org  |u https://mdpi.com/books/pdfview/book/4899  |7 0  |z DOAB: download the publication 
856 4 0 |a www.oapen.org  |u https://directory.doabooks.org/handle/20.500.12854/78804  |7 0  |z DOAB: description of the publication