Genetics of Alzheimer's Disease

• Other Authors: Ibanez, Laura (Editor), Miller, Justin (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Neurosciences; Alzheimer disease; expression quantitative trait loci (eQTL); rare variants; set-based eQTL; SKAT-O; pathways; immune system; inflammation; ROSMAP; ADNI; complement; complement receptor 1; clusterin; late-onset Alzheimer's disease; genetics; neuroinflammation; Alzheimer's disease; cytokines and growth factors; genome-wide association study (GWAS); Polygenic Risk Score (PRS)-based analysis; TOMM40 gene; RNA transcription; pseudogene; mitochondrial dysfunction; ITIM; ITAM; SIGLEC14; SIGLEC5; copy number variation; CNV; GWAS; long non-coding RNA; biomarkers; peripheral system; amyloid β; tau; APOE; TREM2; OMICS; therapeutics; pairwise feature correlation; feature reduction; machine learning; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

This special issue on the genetics of Alzheimer's disease was edited by Drs. Laura Ibanez and Justin Miller in 2021. It contains 10 original articles and reviews that help readers understand specific genetic contributions to Alzheimer's disease and how genetics will play a role in future A...