Multiple Sclerosis Diagnosis and Treatment

• Other Authors: Rivera, Víctor M. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; multiple sclerosis; genetics; disease modifying therapies; generic medicines; association study; reactive oxygen species; NADPH oxidase; CYBB; autoimmunity; axon; cortex; demyelination; mitochondria; myelin; neurodegeneration; oligodendrocyte; progressive multiple sclerosis; daclizumab; relapsing multiple sclerosis; CD25; innate immune system; interleukin-2; drug reaction with eosinophilia systemic symptoms; DRESS; monoclonal antibodies; anti-CD20; Ocrevus; Rituxan; Tysabri; clinical trial; disease modifying therapy; demyelinating diseases; cognitive impairment; cognitive dysfunction; stem cells; autologous hematopoietic; mesenchymal; neuronal; induced pluripotent; human embryonic; pregnancy; post-partum; treatment; neuromyelitis optica spectrum disorders; anti-MOG syndrome; aquaporin 4-IgG; myelin oligodendrocyte glycoprotein; remyelination; outcome measures; biomarkers
• Online Access: DOAB: download the publication; DOAB: description of the publication

Multiple sclerosis (MS) offers important challenges to understanding its complex genetics and molecular and immunological mechanisms, which eventually lead to relapsing and progressive clinical forms and a constellation of clinical manifestations. Along with the progress in knowledge, disease-modify...