Pharmacogenetics to Avoid Adverse Drug Reactions

• अन्य लेखक: López-Fernández, Luis A. (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• विषय: Medicine; 5-fluorouracil; capecitabine; fluoropyrimidine; thymidylate synthase; thymidylate synthase enhancer region; upstream stimulatory factor 1; adverse drug reactions; pharmacogenomics; epistasis; random forest; statin; cardiovascular disease; colorectal cancer; personalised medicine; toxicity; (es)citalopram; drug-gene-interaction; drug-drug-interaction; drug-drug-gene-interaction; the PharmLines initiative; antipsychotic agents; pharmacogenetics; cytochrome P-450 enzyme system; psychotic disorders; precision medicine; direct oral anticoagulants; clinical implementation; atorvastatin; SLCO1B1; HLA; cutaneous adverse drug reaction; SCAR; genetic polymorphism; antiepileptics; CYP450 enzymes; platelet reactivity; single-nucleotide variants; acute coronary syndrome; clopidogrel; genotype; allele; polymorphism; HLA B; CYP2C9*3; cutaneous adverse drug reactions (CADRs); anti-epileptic drugs (AEDS); phenytoin (PHT); genetic risk factors; South India; India; cardiology; adverse events; guidelines; n/a
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Adverse drug reactions are one of the major constraints when using drugs. These adverse reactions can impact healthcare systems as strongly as many prevalent diseases. Identifying DNA variants associated with adverse drug reactions can help personalize medicine and sustain healthcare systems. This b...