Mitochondrial Transport Proteins

• Other Authors: Palmieri, Ferdinando (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Biology, life sciences; hypoxia; resistance to hypoxia; mitochondria; mitochondrial calcium transport; mitochondrial calcium uniporter complex; mitochondrial Ca2+-induced permeability transition pore; cyclophilin D; ATP synthase; disease; error of metabolism; mitochondrial carrier; mitochondrial carrier disease; mitochondrial disease; mitochondrial transporter; membrane transport; mutation; SLC25.; mitochondrial permeability transition; apoptosis; necrosis; ischemia/reperfusion; cancer; neurodegeneration; cyclosporin A; metabolite transport; mitochondrial pyruvate carrier; sideroflexin; TOM; TIM chaperones; TIM22; protein translocation; mitochondrial biogenesis; amino acid; biological function; ion; inner mitochondrial membrane; mitochondrial carrier family; organic acid; substrate specificity; transport mechanism; vitamin; USMG5/DAPIT; glucose-stimulated insulin secretion; glucose-induced expression; membrane subunits of ATP synthase; ATP synthase oligomers mitochondrial cristae morphology; metabolism; metabolic disorders; adult-onset type II citrullinemia (CTLN2); aspartate/glutamate carrier (AGC); animal model; argininosuccinate synthetase (ASS); aversion to carbohydrates; citrin; food taste; neonatal intrahepatic cholestasis caused by citrin deficiency (NICCD); protein-protein interaction; MPC; lifespan; pyruvate metabolism; mitochondrial transport; peroxisomes; carrier; cofactor; ABC transporter; aquaporin; ion channels; potassium channels; ATP; calcium; ROS; potassium channel openers; MCF; function; plant metabolism; plant development; diseases; VDAC1; virus; pancreatic islets; β-cell; diabetes; glucotoxicity; glucolipotoxicity; lipotoxicity; mitochondrial carriers; SLC transporters; SLC25; SLC54; SLC55; LETM; SLC56; sequence analysis; protein targeting; Voltage-Dependent Anion selective Channel; isoforms; oxidative post-translational modification; gene promoter; yeast; bioenergetics; SLC25A1; CIC; CTP; citrate; inflammation; 22.q11.2; NAFLD/NASH; carnitine; carnitine acyl-carnitine carrier; carnitine acyl-carnitine translocase; post-translational modification; solute carrier family 25; SLC25A20; MCU; mitochondrial Ca2+ uniporter; Ca2+ signaling; mitochondrial metabolism; skeletal muscle mitochondria; SLC25A51; NAD+ transporters; NAD; electrophysiology; ATP-dependent potassium channel
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mitochondrial transporters are membrane-inserted proteins which provide a link between metabolic reactions occurring within the mitochondrial matrix and outside the organelles by catalyzing the translocation of numerous solutes across the mitochondrial membrane. They include the mitochondrial carrie...