Redox Imbalance and Mitochondrial Abnormalities in Kidney Disease

• Other Authors: Yan, Liang-Jun (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Pharmacology; diabetic kidney disease; caloric restriction; NADH/NAD+; redox imbalance; mitochondrial homeostasis; mitophagy; oxidative stress; kidney allograft; kidney rejection; ischemia; acute kidney injury (AKI); chronic kidney disease (CKD); tricarboxylic acid (TCA) cycle; mitochondrial metabolism; mitochondrial redox signaling; mitochondrial proteins; oxidative phosphorylation (OXPHOS); fatty acid (FA) β-oxidation; mitochondrial dynamics; biogenesis; diabetes; kidney; mitochondria; Oryza sativa; rice husk; TCA cycle metabolites; kidney diseases; renalase; chronic kidney disease; major adverse cardiovascular outcomes; cadmium; kidney injury; renal toxicity; oxidative damage; proximal tubule; controlled oxygenated rewarming; mitochondrial uncoupling; rewarming injury; temperature paradox; redox; mitochondrial dysfunction; SGLT2; mitochondrial reactive oxygen species; Warburg effect; podocytopathies; mitochondrial oxidative stress; reactive oxygen species (ROS); antioxidant defense; cell death; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The kidney performs important functions in the human body and can inflict either acute kidney injury (AKI) or chronic kidney disease (CKD). AKI can be induced by kidney ischemia, drugs such as cisplatin, and heavy metals such as cadmium and arsenic. CKD can be induced by drugs, heavy metals, hyperte...