Osteoarthritis: From Molecular Pathways to Therapeutic Advances

• Другие авторы: Veronese, Nicola (Редактор)
• Формат: Электронный ресурс Глава книги
• Язык: английский
• Опубликовано: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Предметы: Research & information: general; Biology, life sciences; osteoarthritis; cartilage; type II collagen; matrix metalloproteinases; MMP-13; regulation; inhibitor; NO synthase; Interleukin-1β; chondrocytes; mitochondrial dysfunction; mesenchimal stem cells; chondrocytic commitment; autophagy; miRNAs; hydrostatic pressure; adipokines; visfatin; Wnt/β-catenin; mechanical loading; obesity; microRNA; oxidative stress; vibrational spectroscopy; near-infrared spectroscopy; infrared spectroscopy; Raman spectroscopy; early diagnosis; exercise; physical activity; nutraceuticals; dietary supplements; inflammation; aging; inflammaging; osteochondral explant culture; joint modelling; pharmacological assay; native tissue analysis; hexosamine biosynthetic pathway; cartilage trauma; post-traumatic osteoarthritis; O-GlcNAcylation; glucosamine; cell death; therapy; sex as a biological variable; whole transcriptome sequencing; molecules; TGF-β; SMAD2/3 signaling; linker modifications; meniscus; proteomics; MRM; ECM; celecoxib; glucosamine sulfate; chondroprotection; NF-κB; cytokines; chemokines; pathogenesis; biomarker; chondrocyte; IL-1β; IFNγ, IL-17; IL-4; RNA-Seq; hypertrophy; remodeling; angiogenesis; chondroitin; collagen; methylsulfonylmethane; vitamin C; vitamin D; hyaluronic acid
• Online-ссылка: DOAB: download the publication; DOAB: description of the publication

In this book, we have reported the most recent discoveries and updates regarding molecular pathways in osteoarthritis. In particular, the advances regarding therapeutical options, from a molecular point of view, are largely discussed.