Update on the Management of Non-Obstructive Azoospermia: Current Evidence and Unmet Needs

• Other Authors: Colpi, Giovanni M. (Editor), Caroppo, Ettore (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Pharmacology; nonobstructive azoospermia; micro-TESE; FSH treatment; hormonal treatment; testosterone level; microdissection testicular sperm extraction; non-obstructive azoospermia; management; infertility; intracytoplasmic sperm injection; testicular azoospermia; sperm selection; sperm; cryopreservation; in vitro maturation; azoospermia; diagnosis; male infertility; spermatogenic failure; testis biopsy; sperm retrieval; genetic testing; endocrine evaluation; review; hypogonadism; Sertoli cell-only syndrome; testicular spermatozoa; processing; microfluidics; new technologies; genetics; exome; WES; Y chromosome; cancer; NOA; genes; general health; ICSI; offspring health; microTESE; prediction model; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Azoospermia, defined as the absence of sperm in the ejaculate after examination of the centrifuged specimens, affects about 1% of the male population and 10-15% of infertile men. In about two-thirds of cases, this is caused by severe spermatogenic dysfunction, and it is commonly termed "nonobst...