Role of miRNAs in Cancer Analysis of Their Targetome

• Other Authors: Navarro, Alfons (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Oncology; miR526b; miR655; breast cancer; angiogenesis; lymphangiogenesis; EP4; PI3K/Akt; microRNA-361; EMT; tumor microenvironment; cancer diagnosis; cancer treatment; Bladder cancer; microRNA; genetic marker; progression; ccRCC; prognostic biomarker; miRNA; transcription factor; interplay; microRNAs; exosomes; liquid biopsy; metastasis; cancer; liquid biopsies; tumor; SNAIL (SNAI1) transcription factor; epithelial to mesenchymal transition (EMT); long non-coding RNAs (lncRNAs); circular RNAs; viral miRNAs; EBV; HHV-8; HPV; HCV; HBV; MCPyV; glioblastoma; MGMT; survival; radiotherapy; chemotherapy; temozolomide; translational medicine; oncomiRNA; post-transcriptional regulation; immune regulation; adrenocortical carcinoma; micro RNA; non-coding RNA; thyroid carcinoma; radioactive iodine; drug resistance; prognosis; Burkitt lymphoma; miR-378a-3p; cell growth; pancreatic cancer; radioresistance; personalized medicine; biomarker; target; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

MicroRNAs are the best representatives of the non-coding part of the genome and their functions are mostly linked to their target genes. During the process of carcinogenesis, both dysregulation of microRNAs and their target genes can explain the development of the disease. However, most of the targe...