Method Development and Applications for Reduced-Risk Products in Separation Science

• Other Authors: Aldeek, Fadi (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; Analytical chemistry; on!® nicotine pouches; nicotine; dissolution; release profile; validation; product assessment; smokeless tobacco product; nicotine degradants; nicotine-related impurities; alkaloids; nicotine degradation products; nicotine pouches; reduced-risk products; constituents; method development; method validation; JUUL; aerosol; non-targeted analysis; chemical characterization; ENDS; e-cigarette; GC-MS; LC-HRMS; e-liquid; 2,4-DNPH derivatization; formaldehyde; "hidden formaldehyde"; formaldehyde-containing hemiacetal/acetal adducts; HPHC; 3-hydroxybenzo[a]pyrene; LC-MS/MS; urine; human biomonitoring; derivatization; potentially reduced-risk products; propylene glycol; electronic cigarette; biomarker of exposure; compliance marker; oral tobacco derived nicotine (OTDN) pouches; snus; nicotine release; nicotine dissolution; nicotine extraction; equivalence; modern oral nicotine products; HPHCs; product characterizations; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

In recent years, there has been rapid growth in the availability of innovative, non-combustible products, including oral tobacco-derived nicotine (OTDN) products, heated tobacco products (HTPs), and electronic cigarettes (also referred to as e-vapor products; EVPs). Industry, academic, and governmen...