Molecular imaging in Parkinson's disease
The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychologi...
שמור ב:
| מחבר ראשי: | |
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| פורמט: | אלקטרוני Book Chapter |
| שפה: | אנגלית |
| יצא לאור: |
Firenze
Firenze University Press
2011
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| סדרה: | Premio Tesi di Dottorato
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| נושאים: | |
| גישה מקוונת: | DOAB: download the publication DOAB: description of the publication |
| תגים: |
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| סיכום: | The present work explores brain functional changes in drug-naïve Parkinson's disease (PD) patients by means of molecular imaging techniques. Thirty-one consecutive drug-naïve PD patients from the Neurological Clinic of the University of Flor-ence underwent clinical assessment, neuropsychological assessment, MRI, [123I]FP-CIT SPECT, [18F]FDG PET. First, [18F]FDG-PET was employed to identify in drug-naïve PD patients brain metabolic alteration uniquely related to disease process and not modulated by anti-parkinsonian therapeutic intervention. Second, [18F]FDG-PET and [123I]FP-CIT SPECT were employed together to explore the early functional changes in brain function related to dopaminergic depletion in the putamen and in the caudate nucleus. |
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| תיאור פיזי: | 1 electronic resource (68 p.) |
| ISBN: | 978-88-6655-041-9 9788866550419 9788866550372 9788892736450 |
| גישה: | Open Access |