Anticancer Drugs 2021

• Altri autori: Meegan, Mary J (Redattore), O'Boyle, Niamh M (Redattore)
• Natura: Elettronico Capitolo di libro
• Lingua: inglese
• Pubblicazione: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Soggetti: Research & information: general; Chemistry; thymidylate synthase; cytotoxicity; 1,2,3-triazole; 1,3,4-oxadiazole; 5-fluoruracil; pemetrexed; docking; 3,4'-bis-guanidino; 3-amino-4'-guanidino; diphenyl ether; phenyl pyridyl ether; intramolecular hydrogen bond; cancer cell viability; HL-60; BRAF; apoptosis; thieno[2,3-d][1,2,3]triazine; acetamide; H1299; HER2; EGFR; Bcl-2 inhibitors; Indole-based analogues; benzimidazole; MTT cytotoxic assay; cell cycle analysis; DNA fragmentation; ELISA; solid/lipid nanoparticles; phenstatin; letrozole; tubulin polymerisation inhibitor; aromatase inhibitor; breast cancer; hybrid molecule; dual-targeting molecule; designed multiple ligand; NaMSA; cyclophosphamide; histopathology; testis; urinary bladder; anticancer agents; enantioselective synthesis; gastric adenocarcinoma; tryptophanol; concentration-guided dosing; model informed dosing; physiologically based pharmacokinetics; sorafenib; tyrosil-DNA-phosphodiesterase 1; adamantane; resin acid; TDP1; cytotoxic agents; apoptosis induction; HT-29 cells; MDA-MB-231 cells; mechanism prediction; STAT inhibitors; miR-21; hydrazide derivatives; nitrogen scaffolds; mitoxantrone; cardiotoxicity; inflammation; oxidative stress; age; cumulative dose; Trk; NTRK; tissue-agnostic; larotrectinib; entrectinib; Trk fusion; protein kinase inhibitors; USFDA; cancer; patent review; generic product; doxazosin; MD simulations; combretastatin A-4; cytotoxic activity; hybrid compounds; indazole; mucin; MUC1; MUC16; immunotherapy; cancer vaccine; CAR (chimeric antigen receptor); ADC (antibody-drug conjugate); thiourea; interleukin-6; trypan blue assay; chalcones; exportin-1; covalent binding; CovDock; anticancer activity; xanthone; in vitro; in vivo; isolation; synthesis; heterocyclic compound; benzenesulfonamides; imidazoles; alkylated; colony formation; tumor spheroids; HDAC inhibitors; chalcone; dual inhibitors; carvedilol; kidney; toxicity; 7-deaza-4'-thioadenosine derivatives; multi-kinase inhibitor; anticancer; nucleoside; Imiquimod; drug efflux; multidrug resistance; Toll-Like Receptor; n/a
• Accesso online: DOAB: download the publication; DOAB: description of the publication

The Special Issue "Anticancer Drugs 2021" of Pharmaceuticals is focused on recent significant advances in the design, synthesis, molecular mechanism of action and therapeutic applications of anticancer drugs. This collection of preclinical research papers and reviews includes designed chem...