MicroRNA and Cancer

• Other Authors: Tucci, Paola (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Biology, life sciences; Breast cancer; Hypoxia inducible factor 1-alpha (HIF-1α); MicroRNA (miRNA); miR526b; miR655; Oxidative stress; Migration; Cyclooxygenase-2 (COX-2); Prostaglandin E2 receptor 4 (EP4); PI3K/Akt; adipokines; endometrial cancer; estrogens; hyperinsulinemia; insulin; insulin resistance; insulin signaling; insulin-like growth factors; microRNA; miRNA; ovarian cancer; survival; prognostic factor; serum LDH; blood biomarker; circulating microRNA; plasma; immunotherapy; immune checkpoint inhibitors; metastatic melanoma; hepatocellular carcinoma; metastasis; exosome; bioinformatics analysis; renal cancer; RCC; ccRCC; meta-analysis; miRNAs; normal B-cell development; B-CLL; miRNA-transcription factor network; regulation; biomarker; therapy; prognosis; diagnosis; progression; prediction; smoking; non-small cell lung cancer; methylation; miR-584-5p; YKT6; snoRNA; 2'-O-methylation; pseudouridylation; malignant melanoma; cancer stem cell; stemness; head and neck squamous cell carcinoma; colon cancer; cancer stem cells; microRNAs; deformability; PARP; replication stress; targeted therapy; breast cancer; circulating biomarkers; medulloblastoma; brain tumour; subgroups; stem cells; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

MicroRNAs (miRs) are small noncoding RNAs that function as post-transcriptional regulators of gene expression and have important roles in almost all biological pathways. Deregulated miR expression has been detected in numerous cancers, where miRs act as both oncogene and tumor suppressors. Due to th...