Toxic Metals, Chronic Diseases and Related Cancers

• Other Authors: Satarug, Soisungwan (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Public health & preventive medicine; Trace elements; hair; children; hazardous waste incinerator; Constantí (Catalonia, Spain); blood lead level; boatyard; childhood; lead poisoning; fishing community; lead weights; β2-microglobulin; cadmium; creatinine clearance; glomerular filtration; N-acetyl-β-d-glucosaminidase; nephron mass; nephrotoxicity; trace elements; autopsy tissues; temporal trends; creatinine excretion; glomerular filtration rate; lead; kidney; endocytosis; metallothionein; flow cytometry; proximal tubule epithelial cells; OGTT; minimal model; glucose response mechanism; genotoxicity; aluminum chloride; rats; food; farmer; PTWI (provisional tolerable monthly intake); TWI (tolerable weekly intake); Monte Carlo simulation; mercury; obesogen; lipid profiles; hyperlipidemia; elevated liver enzymes; hexavalent chromium [Cr(VI)]; mitochondrial fragmentation; dynamin-related protein 1 (Drp1); mitochondrial respiratory chain complex I (MRCC I); reactive oxygen species (ROS); blood lead; cellular immunity; phagocytosis; humoral munity; immunosuppression; insulin; diabetes; hyperglycemia; hyperinsulinemia; lipogenic; β-cell toxicity; stroke; cerebrovascular accident; heavy metal; rare earth element; case-control study; mortality; lifetime cadmium intake; renal diseases; urinary cadmium; a follow-up study; diet; kidney function; chronic kidney disease; threshold limit; tolerable intake level; heavy metals; birth weight; preterm birth; diet pattern; Mediterranean diet; pregnancy; toxic metals; reproduction; testicular and ovarian structure; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Long-term exposure to environmental toxicants is estimated to account for 70-90% of the risks of acquiring chronic ailments. Presently, chronic kidney disease and infertility affect a significant proportion of the world population, while research data indicate that exposure to toxic metals may contr...