Redox-Active Molecules as Therapeutic Agents

• Other Authors: Fernandes, Ana Sofia (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Biology, life sciences; non-small cell lung cancer; cisplatin; apurinic/apyrimidinic endonuclease 1; E3330; cytotoxicity; apoptosis; migration; invasion; oxidative stress; sildenafil; DNA damage; systemic sclerosis; bioactivity-based assays; cyanidin; metabolomics; Rubus genus; (poly)phenols; yeast-based discovery platform; withanolide; breast cancer; mitochondrial reactive oxygen species; peroxiredoxin 3; pro-oxidant therapy; thiostrepton; GSH; Cysteamine; N-acetyl cysteine; KEAP1; NRF2; ATF4; adipose-derived mesenchymal stem cell; amniotic membrane-derived mesenchymal stem cell; antioxidants; assisted reproductive technology; conditioned medium; embryo; in vitro culture; in vitro fertilization; BAPN; cell invasion; EMT; lysyl-oxidase; lysyl-oxidase like 2; metastases; inhibitors; doxorubicin; chemoresistance; redox signaling; nuclear factor erythroid 2-related factor 2 (Nrf2); cancer therapy; hydrogen sulfide; reactive oxygen species; H2S donors; cardiorenal syndrome; thiosulfate; selenium-enriched Enterococcus faecium; selenium-enriched Streptococcus thermophilus; antioxidant capacity; glutathione reductase; glutathione peroxidase; CD IGS rats; lactic acid bacteria; verbascoside; hypercholesterolemia; prostate cancer; curcumin; carnosic acid; cell cycle; OxPhos; SGK1; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Oxidative stress and altered redox signaling have been described in a plethora of pathological conditions. Redox-active molecules can thus potentially be used to modulate the etiology/progression of such diseases. Recent advances in molecular biology and pharmacology have strengthened this area of r...