Novel Strategies in the Development of New Therapies, Drug Substances and Drug Carriers

• その他の著者: Kutner, Andrzej (編集者), Brown, Geoffrey (編集者), Kallay, Enikö (編集者)
• フォーマット: 電子媒体 図書の章
• 言語: 英語
• 出版事項: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• 主題: Research & information: general; Chemistry; alpha-ketoglutarate; cell cycle; apoptosis; JNK; cell migration; cell invasion; TGF-β; VEGF; glycoconjugates; methotrexate; cancer treatment; glucose metabolism; drug design and discovery; anticancer drugs; targeted therapy; Warburg effect; antidepressants; pyrido[1,2-c]pyrimidines; dual 5-HT1A/SERT activity; drug design; anticancer activity; lung cancer; resveratrol; PRI-2191; vitamin D; active substance delivery systems; biomedical hydrogels; active substance-controlled release; genistein; hydrogels for cosmetology; hydrogels for dermatology; transdermal active substance delivery systems; histone deacetylase (HDAC); depression; biomarker; anti-depressant therapy; human DNA topoisomerase; cancer; drug; molecular docking; synthesis; fluorine; vitamin D3; metabolite; A-ring; CD-ring; side-chain; nanoparticles; molecular modeling; oxidation mechanisms; electrochemistry; MALDI; spectroscopic data; cytotoxic study; self-assembled monolayer; gold electrode; multimodal activity; calcium-sensing receptor; enantiomer; calcimimetic; calcilytic; colon cancer; stereospecificity; HT-29; IL-8; inflammation; cyclooxygenase; 1,2,4-triazole; pyridazinone; SAR; anti-inflammatory activity; antioxidant activity; ADME; anticancer drug; antimicrobial peptide (AMP); dermaseptin; frog skin peptides; LHRH; prostate cancer; Phyllomedusa bicolor; therapeutic peptides; copper (II) complexes; thiourea; cytotoxic activity; proteome analysis; antimicrobial activity; major latex protein; Chelidonium majus; greater celandine; defense-related proteins; alkaloids; cancer cells; vitamin D receptor; split luciferase-based biosensor; CYP24A1-dependent metabolism; CYP27B1; rickets; genome editing; vitamin D biology and action; transcription; ChIP-chip analysis; distal enhancers; histone H3 acetylation; RNA polymerase II; analogue actions at genes; vitamin D hormone (1,25(OH)2D3); latex; antiviral proteins; antimicrobial compounds; cytotoxicity; drug discovery; CRISPR/Cas9; tetrahydro-β-carbolines; Plasmodium falciparum (P. falciparum); antimalarial; antiparasitic agents; hemolysis; vitamin D analogs; 25 vitamin D 24-hydroxylase; CYP24A1; proliferation; high-grade serous ovarian cancer cells; gold; Au(III) complex; colorectal cancer; organometallic; cancer therapy; metallodrugs; n/a
• オンライン･アクセス: DOAB: download the publication; DOAB: description of the publication

This book is conceived to promote synergy between research and industrial activities in the design and development of new drugs and, therefore, is not limited to any specific aspect of development. It covers the entire process from the identification of a molecular target, studies of drug-protein in...