Enhancing Mesenchymal Stem Cells (MSCs) for Therapeutic Purposes

• Other Authors: Ylostalo, Joni H. (Editor), Durand, Nisha C. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel 2022
• Subjects: Medicine; cell therapy; immunomodulation; polyunsaturated fatty acid; CD206; phagocytosis; mesenchymal stem cells; Vadadustat; AKB-6548; preconditioning; priming; secretome; chemotaxis; Wharton's jelly mesenchymal stem cells; umbilical cord; oxygen conditions; secretory profile; neuroprotection; mesenchymal stromal cells; 3D culture; neurospheres; spheroids; pluripotency; neural; quiescence; mesothelioma; malignant pleural mesothelioma (MPM); liver cirrhosis; placenta-derived mesenchymal stem cells; WKYMVm; combination therapy; iPSC-derived MSCs; iMSC secretome; pre-conditioning; angiogenesis; IFN-γ; hypoxia; potentiation of iMSC efficacy; nanofiber-hydrogel composite; spinal cord injury; inflammation; macrophages; secondary injury; astrocytes; axon growth; adipose tissue-derived stem cells (ASCs); autophagy; rapamycin; 3-methyladenine; immunosuppression; exosome; engineered cardiac patches; adipose-derived stem cell; paracrine potential; osteogenic differentiation; hepatocyte growth factor; fibroblast growth factor 2
• Online Access: DOAB: download the publication; DOAB: description of the publication

The regenerative and immunomodulatory properties of mesenchymal stem cells (MSCs) have made these cells the focus of multiple pre-clinical studies and clinical trials. While the results from these clinical studies have established that MSCs are safe, the efficacy of these cells is not as well-establ...