Recent Advances in Volatile Organic Compound Analysis as Diagnostic Biomarkers

• Other Authors: Drabińska, Natalia (Editor), Lacy Costello, Ben de (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; liquid-liquid extraction; volatile compounds; urine; method optimization; GC-MS; 1H-NMR; iron deficiency anaemia; iron supplementation; volatile organic compounds (VOCs); intestinal metabolome; gut microbiome; CDH; microbiome; VOCs; spiroergometry; outcome; exhaled breath; eNose; smoking; asthma; COPD; NTD-GC-MS; breath; lung cancer; biomarkers; volatile organic compounds; urine analysis; comprehensive two-dimensional gas chromatography; kidney diseases; urinary biomarkers; hepatocellular carcinoma; diagnosis; headspace analysis; untargeted analysis; breath analysis; cancer biomarkers; volatolomics; whole grain; rye; comprehensive two-dimensional gas chromatography-mass spectrometry; dietary fiber; e-nose; electronic nose; breathing rhythm; mechanical ventilation; anesthesia; supplemental oxygen; oxygen toxicity; lipid peroxidation; volatile aldehydes; pentanal; hexanal; classification models; dairy cows; fecal headspace; Mycobacterium avium ssp. paratuberculosis (MAP); paratuberculosis; random forest; stable air; volatile organic compound (VOC); biomarker; MCC-IMS; ventilator-induced lung injury; metabolome; feces; neonates; fermentation; protein; carbohydrate; short chain fatty acid; metabolites; volatile organic compound; acute gastritis; antibiotic treatment; treatment dynamics: microbiota; mid-infrared spectroscopy; short-chain fatty acid; alpha-keto acid; Helicobacter pylori; MOX sensors; low sensing chamber volume; calibration transfer; standard samples; piecewise direct standardization; correlation alignment; breath sampling; pattern recognition
• Online Access: DOAB: download the publication; DOAB: description of the publication

Volatile organic compounds (VOCs) are a diverse group of carbon-based molecules that are volatile at ambient temperatures and are emitted by an organism as a result of metabolic processes of cells and associated microbiome. The qualitative and quantitative profile of VOCs in biological fluids can va...