New Insights into Molecular Mechanisms Underlying Neurodegenerative Disorders

• Other Authors: Villa, Chiara (Editor), Paudel, Yam Nath (Editor), Piperi, Christina (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Biology, life sciences; Parkinson's disease; schizophrenia; Mendelian randomization; genetics; TLRs; neuroinflammation; neuroprotection; neurodegeneration Parkinson's disease; Alzheimer's disease; aducanumab; LMICs; APOE; burden of disease; treatment cost; Parkinson disease; epigenetics; DNA methylation; histone modifications; lcRNAs; environmental toxins; smoking; pesticides; coffee; diagnosis; stochasticity; space-time; entropy; neurodegeneration; EEG; MEG; graph theory; Alzheimer; Parkinson; Interleukin-37; central nervous system diseases; inflammatory; anti-inflammatory; cytokines; gut microbiota; gut-brain axis; dysbiosis; homology modelling; LOMETS; MUSTER; iGEMDOCK; AutoDock vina; MPTP model; mice; tyrosine hydroxylase; phosphorylation; neuroplasticity; Alzheimer's disease viral hypothesis; human herpesviruses; amyloid beta (Aβ); tau protein; n/a; levodopa-induced dyskinesia; circular RNA; next-generation sequencing
• Online Access: DOAB: download the publication; DOAB: description of the publication

Neurodegenerative disorders encompass a broad range of sporadic and/or familial debilitating conditions characterized by the progressive dysfunction and loss of selective neuronal populations, determining different clinical phenotypes. Emerging research data indicate an interplay of genetic factors...