Micro/Nanofluidic and Lab-on-a-Chip Devices for Biomedical Applications

• Other Authors: Carvalho, Violeta (Editor), Teixeira, Senhorinha de Fátima Capela Fortunas (Editor), Ribeiro, João (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; protein biomarker; microarray; microfluidic cassette; multiplex measurement; immunoassay; point-of-care testing; microfluidic device; small intestine; ex vivo; histology; embedded resin; sectioning; peptide biosensor; lab-on-a-chip; label-free detection; peptide aptamers; protein biomarkers; microfluidic biochip; troponin T; computational simulations; drug discovery; organ-on-a-chip; microfluidic devices; preclinical models; numerical simulations; automation; non-enzymatic; DNA amplification; L-DNA; microfluidic; fluorescence; paper microfluidics; sweat; sensing; hydrogels; lactate; osmotic pumping; evaporation; capillary; wicking; biochemical assay; microfluidics; cell trap; RBC; evolutionary algorithm; generative design; artificial intelligence; organ-on-chip; liver-on-chip; liver disease; multi-level microfluidic device; live cell imaging; long-term microscopy imaging; focus drifting; immersion oil viscosity; bacterial population dynamics; single-cell studies; E. coli; mother machine; computational fluid dynamics; cancer-on-chip; xenograft; colorectal cancer; pharmacodynamics; pharmacokinetics; drug efficacy; oxaliplatin; microfabrication; microphysiological system; biophysical stimuli; biochemical stimuli; in vitro cell culture; cortical neurons; hippocampal neurons; electrical stimulation; Micro-Electrode Arrays; engineered neuronal networks; polydimethylsiloxane; microchannels; in vivo micro bioreactor; additive manufacturing; poly-(ethylene glycol)-diacrylate; biocompatibility; COVID-19; diagnosis; image analysis; PCR; SARS-CoV-2; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

Recently, microfluidic, nanofluidic and lab-on-a-chip devices have gained particular attention in biomedical applications. Due to their advantages, such as miniaturization, versatility, ease of use, cost-effectiveness, and the potential to replace animal models for drug development and testing, thes...