Molecular Mechanisms and Therapies of Colorectal Cancer

• その他の著者: Cave, Donatella Delle (編集者), Ottaiano, Alessandro (編集者)
• フォーマット: 電子媒体 図書の章
• 言語: 英語
• 出版事項: Basel MDPI - Multidisciplinary Digital Publishing Institute 2023
• 主題: Medicine; Oncology; colorectal cancer; miRNA; ceRNA; lncRNA; circRNA; sponging; noninvasive biomarkers; MiR-199b; tumor suppressor; prognosis; LARC; HOX; HOXB9; colorectal liver metastases; metastatic colorectal cancer; structural variants; common fragile sites; platinum therapy; stalled replication fork; surgical oncology; liver regeneration; immunology; hepatic tissue-resident memory T cells; liver neoplasms; neoplasm metastasis; proteomics; biomarkers; mass spectrometry; microRNA; hypoxia; hypoxia-regulated microRNAs; fatty acid synthase; lipid metabolism; colorectal cancer initiation; Apc mutation; epigenetics; methylation; biomarker; S-Adenosylmethionine; breast cancer; Notch; metastasis; EMT; targeted sequencing; inflammatory bowel diseases; colitis-associated cancer; phosphatidylinositol 3-kinase; sortilin; neurotensin; neurotensin receptor-3; soluble sortilin; cell signaling; cell morphology; colorectal carcinoma; early onset CRC; multi-omics; lymphovascular invasion; perineural invasion; DNA damage repair; DNA replication repair; MMR; base excision repair; FASN; CTLA4; HAVCR2; TGF-β signaling; targeting therapy; immune-suppressive; barrier properties; colon; heterogeneity; cytokines; tumor necrosis factor alpha; interleukin 10; tight junction proteins; 1,2-dimethylhydrazine; rat; epithelial-to-mesenchymal transition; tumor-associated macrophages
• オンライン･アクセス: DOAB: download the publication; DOAB: description of the publication

Colorectal cancer (CRC) is currently the third leading cause of cancer-related mortality, with 1.9 million incidence cases and 0.9 million deaths worldwide. The global number of new CRC cases is predicted to reach 3.2 million in 2040, based on the projection of aging, population growth, and human de...