BRCA1 and BRCA2 Mutations Diagnostic and Therapeutic Implications

• Other Authors: Valarmathi, Mani T. (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: IntechOpen 2023
• Subjects: Medical genetics; Pre-clinical medicine: basic sciences
• Online Access: DOAB: download the publication; DOAB: description of the publication

Mutations in the BRCA1/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pa...