BRCA1 and BRCA2 Mutations Diagnostic and Therapeutic Implications

• अन्य लेखक: Valarmathi, Mani T. (संपादक)
• स्वरूप: इलेक्ट्रोनिक पुस्तक अध्याय
• भाषा: अंग्रेज़ी
• प्रकाशित: IntechOpen 2023
• विषय: Medical genetics; Pre-clinical medicine: basic sciences
• ऑनलाइन पहुंच: DOAB: download the publication; DOAB: description of the publication

Mutations in the BRCA1/2 genes are the most common cause of hereditary breast and ovarian cancer (HBOC), and HBOC is an autosomal dominant cancer predisposition syndrome. Individuals with HBOC have a high risk for breast and ovarian cancers and a moderate risk for other cancers, such as prostate, pa...