A Personalized Medicine Approach to the Diagnosis and Management of Autism Spectrum Disorder

• Other Authors: Frye, Richard E. (Editor), Boles, Richard (Editor), Rose, Shannon (Editor), Rossignol, Daniel (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Medicine; Neurosciences; fecal metabolites; ASD; microbiome; gastrointestinal symptoms; Fisher Discriminant Analysis; digital biomarkers; wearables; time series analysis; autism; social dyads; socio-motor parameters; network connectivity; non-linear complex dynamics; stochastic analysis; autism spectrum disorders; copy number variants; females; Array-Comparative Genomic Hybridization (Array-CGH); autism spectrum disorder; Ehlers-Danlos syndrome; hypermobility spectrum disorders; autonomic disorder; mast cell activation syndrome; genetic testing; chromosomal microarray analysis; whole exome sequencing; whole genome sequencing; clinical utility; polygenic risk scores; Temple Grandin; biomarker; omics; precision medicine; proteomics; transcriptomics; epigenetics; metabolomics; patient stratification; mitochondria; oxidative stress; prenatal environment; immune dysfunction; immunoglobulin G; intravenous immunoglobulin; energy metabolism; fatty acid oxidation; acyl-carnitines; resveratrol; integrative; model; concomitant; condition; disorder; autism spectrum disorder (ASD); genomics; personalized treatment strategy; single nucleotide polymorphisms; clinical decision support tool; ADHD; PANDAS; OCD; anxiety; folate receptor alpha; folates; pregnancy; brain development; fetal development; cobalamin; glutathione; methylation; methylcobalamin; redox metabolism; locked-in network syndrome; resting-state functional magnetic resonance imaging; temporal lobe epilepsy; amygdala; brain; COVID-19; children; cytokines; flavonoids; inflammation; luteolin; mast cells; microglia; SARS-CoV-2; stress; nutraceuticals; survey; vitamins; minerals; B12; folinic acid; quality of life; parents; intervention; systematic review; medical claims; logistic regression analysis; retrospective analysis; associated risk; monoamine neurotransmitters; neurotransmitter deficiency; cerebral folate deficiency; folate receptor alpha autoantibodies; leucovorin; α-amylase; cortisol; heart rate variability; neuromodulation; sleep anxiety; transdermal electrical neuromodulation; neurostimulation; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

This collection of articles provides an overview of the current and future methods for applying a personalized medicine approach to the diagnosis, management, and treatment of autism spectrum disorder.