Anticancer Inhibitors

• Other Authors: Fantacuzzi, Marialuigia (Editor), Ammazzalorso, Alessandra (Editor)
• Format: Electronic Book Chapter
• Language: English
• Published: Basel MDPI - Multidisciplinary Digital Publishing Institute 2022
• Subjects: Research & information: general; Chemistry; breast cancer; tamoxifen; LY294002; synergism; apoptosis; cell cycle; tea (Camellia sinensis) flowers; BTFS; A2780/CP70 ovarian cancer cells; S phase cell cycle arrest; nicotinamide phosphoribosyltransferase; NAD+ biosynthesis; inhibitor; azacyclohexane; anticancer drug; drug design; enthalpy effect; NSCLC; Cathepsin K; cell proliferation; cell migration; cell invasion; mTOR; isatin-hydrazones; cytotoxicity; CDK2 inhibitor; ATP competitive inhibitor; ADME analysis; receptor tyrosine kinases; protein-protein interactions; protein engineering; directed evolution; angiogenesis; binding affinity; agonistic activity; saponins; phytochemicals; tea (Camellia sinensis) flower; ovarian cancer; autophagy; ZMYND8; tumorigenesis; epigenetic regulation; pro-oncogenic effects; tumor suppression; tacrine-coumarin derivatives; DNA; topoisomerases I; II; lung carcinoma cells; A549; chemotherapy; prodrug; drug targeting; overexpressed enzymes; ADC; ADEPT; GDEPT; LEAPT; PROTAC; cyclin-dependent kinase; cancer; resistance; small molecule inhibitors; PROTACs; statins; pancreatic cancer; DNA microarray; pitavastatin; cerivastatin; simvastatin; fluvastatin; atorvastatin; pravastatin; HMG-CoA reductase inhibitors; n/a
• Online Access: DOAB: download the publication; DOAB: description of the publication

The word "cancer" is associated with at least 100 different pathologies, depending on the organ involved and the type of tumor developed. Cancer is a complex disease involving multiple pathogenetic mechanisms. Characterization of different types of cancers, which distinguishes them from he...