Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells

Effect of Overexpression of the Brain-Specific Na+/Ca2+ Exchanger Splice Variant NCX1.5 on NO Cytotoxicity in HEK293 Cells

Abstract.: Nitric oxide (NO) induces cytotoxicity in neuronal and glial cells via activation of the Na+/Ca2+ exchanger (NCX). This study examined the role of the predominant brain-specific NCX splice variant NCX1.5 in NO-induced cytotoxicity in the HEK293 cell expression system. Cells were transfect...

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Main Authors: Yuki Ota (Author), Takuya Kawanai (Author), Ryo Watanabe (Author), Akira Nishimura (Author), Yukio Ago (Author), Kazuhiro Takuma (Author), Toshio Matsuda (Author)
Format: Book
Published: Elsevier, 2013-01-01T00:00:00Z.
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