Fibroblast Growth Factor 21 Ameliorates NaV1.5 and Kir2.1 Channel Dysregulation in Human AC16 Cardiomyocytes

• Main Authors: Jiamin Li (Author), Yuanshi Li (Author), Yining Liu (Author), Hang Yu (Author), Ning Xu (Author), Di Huang (Author), Yadong Xue (Author), Sijia Li (Author), Haixin Chen (Author), Jiali Liu (Author), Qingsui Li (Author), Yiming Zhao (Author), Ronghao Zhang (Author), Hongru Xue (Author), Yuehang Sun (Author), Ming Li (Author), Pengyu Li (Author), Mingbin Liu (Author), Zhen Zhang (Author), Xin Li (Author), Weijie Du (Author), Ning Wang (Author), Baofeng Yang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Infarcted myocardium is predisposed to cause lethal ventricular arrhythmias that remain the main cause of death in patients suffering myocardial ischemia. Liver-derived fibroblast growth factor 21 (FGF21) is an endocrine regulator, which exerts metabolic actions by favoring glucose and lipids metabo...