Pharmacokinetic-pharmacodynamic modelling of atazanavir in hair among adolescents on antiretroviral treatment in Zimbabwe

• المؤلفون الرئيسيون: Bernard Ngara (مؤلف), Simbarashe Zvada (مؤلف), Tariro Dianah Chawana (مؤلف), Charles Fungai Brian Nhachi (مؤلف), Simbarashe Rusakaniko (مؤلف)
• التنسيق: كتاب
• منشور في: BMC, 2021-05-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Abstract Background Drug potency is a pharmacological parameter defining dose or concentration of drug required to obtain 50% of the drug's maximal effect. Pharmacokinetic-pharmacodynamic modelling and simulation allows estimation of potency and evaluate strategies improving treatment outcome....