Herb-drug interactions of silybinin and cilofexor in beagle dogs based on pharmacokinetics by UPLC-MS/MS

• Main Authors: Xinyi Wei (Author), Yanding Su (Author), Qian Cheng (Author), Songmao Liang (Author), Tingping Zhang (Author), Lengxin Duan (Author), Xiuwei Shen (Author), Xiangjun Qiu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: A remarkably sensitive, accurate, and efficient ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS) approach was developed as a facile and expeditious method for measuring cilofexor concentration in beagle dogs, the herb-drug interactions between silybinin and ci...