Prediction of Drug Targets for Specific Diseases Leveraging Gene Perturbation Data: A Machine Learning Approach

• Huvudskapare: Kai Zhao (Författare, medförfattare), Yujia Shi (Författare, medförfattare), Hon-Cheong So (Författare, medförfattare)
• Materialtyp: Bok
• Publicerad: MDPI AG, 2022-01-01T00:00:00Z.
• Ämnen: article
• Länkar: Connect to this object online.

Identification of the correct targets is a key element for successful drug development. However, there are limited approaches for predicting drug targets for specific diseases using omics data, and few have leveraged expression profiles from gene perturbations. We present a novel computational appro...